{"id":"W4406608472","doi":"10.1590/1984-3143-ar2024-0037","title":"Swine clones: potential application for animal production and animal models","year":2025,"lang":"en","type":"review","venue":"Animal Reproduction","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Somatic cell nuclear transfer; Cloning (programming); Biology; Homologous recombination; Genetically modified organism; Somatic cell; Genetics; Recombinant DNA; Genome editing; Limiting; Molecular cloning; Gene; Computational biology; Biotechnology; CRISPR; Computer science; Blastocyst; Gene expression; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003637704,0.0003825178,0.000577301,0.0001369513,0.0001426257,0.00003828726,0.0001360911,0.0003787033,0.000001599383],"category_scores_gemma":[0.0002392472,0.0003872238,0.0002522518,0.0001991981,0.00005066643,0.00001466427,0.000117866,0.0001604983,0.000002564086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003484436,"about_ca_system_score_gemma":0.0001387039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001197832,"about_ca_topic_score_gemma":0.000005697389,"domain_scores_codex":[0.9976158,0.00004155242,0.0004921196,0.001448994,0.0001281686,0.0002733988],"domain_scores_gemma":[0.9989244,0.000008673346,0.0002045665,0.0006326616,0.0001702062,0.00005947254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005224355,0.0001278502,0.000003935983,0.01551404,0.000258515,0.000001061032,0.00002579746,0.0003726825,0.1313156,0.0003675252,0.002763981,0.8487266],"study_design_scores_gemma":[0.0002470714,0.001055198,0.00003704779,0.001056766,0.0009747545,0.0002209098,0.00003063916,0.0005700113,0.01384925,0.0001116407,0.9811363,0.0007104396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001897331,0.9750137,0.02050073,0.0001340921,0.0004501004,0.001841045,0.00004304707,0.00005731341,0.00006262547],"genre_scores_gemma":[0.02032858,0.9730266,0.001312927,0.000008569988,0.003262401,0.0005880238,0.0006935539,0.00006606834,0.0007133015],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9783723,"threshold_uncertainty_score":0.999858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824685892740939,"score_gpt":0.3444736834534987,"score_spread":0.3262268245260893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}