{"id":"W4406624486","doi":"10.3390/biom15010143","title":"Sex-Specific Differences in the Pathophysiology of Hypertension","year":2025,"lang":"en","type":"review","venue":"Biomolecules","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Endocrinology; Internal medicine; Medicine; Endothelial dysfunction; Pathophysiology; Pathophysiology of hypertension; Adipose tissue; Hormone; Fatty liver; Angiotensin II; Disease; Physiology; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140286,0.0002021426,0.001344958,0.0002671897,0.0000262687,0.00000591384,0.0001523891,0.0002326057,0.00001781812],"category_scores_gemma":[0.00006911479,0.00009973808,0.0002952427,0.0003911818,0.0001368426,0.000008510867,0.00004463735,0.000164746,0.00001578989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002014948,"about_ca_system_score_gemma":0.0001577827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001430488,"about_ca_topic_score_gemma":0.000002248635,"domain_scores_codex":[0.9987814,0.0002230836,0.0004134653,0.0002499285,0.0002021885,0.0001299471],"domain_scores_gemma":[0.9991547,0.0002924019,0.0001229765,0.0003443302,0.00005802935,0.00002760122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001387494,0.0001043106,0.000006477719,0.002889846,0.00002580175,0.0001123413,0.00002714443,5.261162e-9,0.0004158591,0.0007868884,0.0007264998,0.9948909],"study_design_scores_gemma":[0.000275374,0.0001383643,0.001113037,0.01016027,0.0002596401,0.0001058445,0.00006933117,0.000006629719,0.00001985914,0.0001490896,0.987575,0.0001275627],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004379858,0.998078,0.00001544297,0.0002294415,0.00008075849,0.0004575568,0.00001152966,0.00001118868,0.0006780845],"genre_scores_gemma":[0.002260848,0.9970419,0.00008388124,0.0002012234,0.00005498284,0.00002394514,0.00008516775,0.00001053608,0.0002375551],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9947634,"threshold_uncertainty_score":0.4067201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09999615862464989,"score_gpt":0.3213850248199974,"score_spread":0.2213888661953475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}