{"id":"W4406629123","doi":"10.1101/2025.01.20.633641","title":"A cholinergic spinal pathway for the adaptive control of breathing","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Cholinergic; Neuroscience; Breathing; Control of respiration; Medicine; Computer science; Psychology; Anesthesia; Internal medicine; Respiratory system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001120693,0.0002858922,0.0001554449,0.0001695585,0.0002012963,0.0003841294,0.0002513035,0.0003428272,0.001538551],"category_scores_gemma":[0.00007716045,0.00008744945,0.000165825,0.00007496209,0.0002576495,0.0002365008,0.0003176902,0.0005801478,0.0002897895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003018245,"about_ca_system_score_gemma":0.0003514505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009291862,"about_ca_topic_score_gemma":0.001331806,"domain_scores_codex":[0.9999557,0.00000430022,0.000003299559,0.00001181095,0.00001485218,0.00001000134],"domain_scores_gemma":[0.9999459,0.000005350601,0.00001451894,0.000005494805,0.00001142001,0.00001726805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002806708,0.00000980506,0.0002581173,0.00003115516,0.000003543255,0.00005634727,0.000009481121,0.00007758835,0.99647,0.0004346677,0.00004007626,0.002581225],"study_design_scores_gemma":[0.00003334289,0.0005687289,0.04133634,0.00007548944,0.00004219743,0.0008351606,0.000132699,0.005112406,0.9458734,0.001072573,0.004903096,0.00001448181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622178,0.004713977,0.025015,0.0004657031,0.00007733318,0.00006646058,0.0003760762,0.0002267129,0.006841024],"genre_scores_gemma":[0.9873962,0.001141638,0.005404257,0.00008715842,0.00001180167,0.00003453353,0.0001463893,0.00001063071,0.005767389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538551,"threshold_uncertainty_score":0.005146921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03326537854799432,"score_gpt":0.259333644452327,"score_spread":0.2260682659043327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}