{"id":"W4406678440","doi":"10.1177/12034754241304729","title":"A Multicentre Evaluation of a Ceramide-Containing Hydrating Cream-to-Foam Cleanser and Facial Moisturizing Lotion for Improving Topical Treatment Tolerability in Facial Acne","year":2025,"lang":"en","type":"article","venue":"Journal of Cutaneous Medicine and Surgery","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Windsor Clinical Research; Victoria Park; University of Toronto; University of British Columbia","funders":"","keywords":"Medicine; Tolerability; Acne; Cleanser; Lotion; Dermatology; Cosmeceuticals; Sensitive skin; Adjunctive treatment; Moisturizer; Topical medication; Topical agents; Seborrhoeic dermatitis; Adverse effect; Cosmetics; Internal medicine; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00396671,0.001253334,0.002074086,0.0006003705,0.0009502541,0.0008243714,0.0008691736,0.001402964,0.003268436],"category_scores_gemma":[0.003760987,0.0006589938,0.00273596,0.0004951948,0.000817174,0.0008843594,0.0006133184,0.001399556,0.0004714491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009127415,"about_ca_system_score_gemma":0.002063902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002752521,"about_ca_topic_score_gemma":0.005894767,"domain_scores_codex":[0.9978643,0.0009886281,0.000203205,0.0003771976,0.0003456311,0.0002210664],"domain_scores_gemma":[0.9979527,0.0004003056,0.0004916654,0.0002943868,0.0003446351,0.000516262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6849128,0.2100217,0.0111041,0.001971361,0.00420698,0.0002072113,0.0006264757,0.0008113568,0.02126259,0.00008933013,0.0009497922,0.0638364],"study_design_scores_gemma":[0.208176,0.748556,0.0387235,0.00006204491,0.001548762,0.0001013916,0.0001493043,0.000403157,0.001430553,0.00004032395,0.0007606431,0.00004828967],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99543,0.0007391384,0.0003436734,0.00007989865,0.00007575113,0.002686723,0.0003208638,0.00002594328,0.0002980629],"genre_scores_gemma":[0.9934227,0.0006584068,0.00205681,0.0002752618,0.0001141619,0.002410399,0.0003732523,0.00001277595,0.0006761583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00396671,"threshold_uncertainty_score":0.02097821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04186586282008759,"score_gpt":0.3366788018387899,"score_spread":0.2948129390187023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}