{"id":"W4406687800","doi":"10.1093/ecco-jcc/jjae190.0844","title":"P0670 Efficacy of subcutaneous guselkumab induction therapy by baseline demographics and concomitant medications in participants with moderately to severely active Crohn’s disease: Results from the phase 3 GRAVITI study","year":2025,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Concomitant; Demographics; Crohn's disease; Internal medicine; Disease; Physical therapy; Demography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002348935,0.0006869154,0.001313544,0.0001981591,0.0002891529,0.0006756239,0.0004681386,0.0007219693,0.002609313],"category_scores_gemma":[0.001683339,0.0002539014,0.001325596,0.0003696492,0.0005229824,0.0005569901,0.0004877587,0.001300935,0.000428346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003687202,"about_ca_system_score_gemma":0.0006438863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003934417,"about_ca_topic_score_gemma":0.001028902,"domain_scores_codex":[0.9989544,0.0006160897,0.00006411037,0.0001246441,0.0001513051,0.00008937113],"domain_scores_gemma":[0.9987383,0.0003200287,0.0004074235,0.0001000788,0.0001087093,0.0003254611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7642952,0.008540158,0.08510001,0.001133444,0.003342942,0.0001166854,0.0002436669,0.0006359178,0.02413621,0.0001413076,0.003082194,0.1092323],"study_design_scores_gemma":[0.1599421,0.3669966,0.4575427,0.0001203685,0.004040794,0.0003723869,0.0001901743,0.001384912,0.004555685,0.0003672633,0.004409346,0.00007765808],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940374,0.003128559,0.000245827,0.0002311514,0.00003677289,0.0003831176,0.0009367822,0.00004400719,0.0009564245],"genre_scores_gemma":[0.9969571,0.000472275,0.0004756346,0.0002934299,0.0001002578,0.0003663307,0.0009277735,0.000008875269,0.0003982476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002609313,"threshold_uncertainty_score":0.0124225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522945693115502,"score_gpt":0.2949481911564688,"score_spread":0.2797187342253138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}