{"id":"W4406690958","doi":"10.1200/jco-24-01829","title":"Postoperative Radiotherapy ± Cetuximab for Intermediate-Risk Head and Neck Cancer","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network; Centre Hospitalier de l’Université de Montréal","funders":"National Cancer Institute; NRG Oncology; Eli Lilly and Company","keywords":"Medicine; Cetuximab; Head and neck cancer; Internal medicine; Hazard ratio; Radiation therapy; Oncology; Cancer; Head and neck squamous-cell carcinoma; Toxicity; Exact test; Larynx; Surgery; Confidence interval; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"nonrandomized_trial","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005704454,0.0001787963,0.0005766972,0.0001229656,0.0001671219,0.0001678824,0.0002199683,0.0001715257,0.002052657],"category_scores_gemma":[0.0005150545,0.00006834579,0.0003597809,0.0001136064,0.0001685483,0.0001425196,0.0001431631,0.000347387,0.0002152852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003225995,"about_ca_system_score_gemma":0.0005035361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006930712,"about_ca_topic_score_gemma":0.002629038,"domain_scores_codex":[0.999806,0.00006951272,0.0000187132,0.00003494885,0.00003697818,0.0000339094],"domain_scores_gemma":[0.9998159,0.0000493823,0.00004659136,0.00001575706,0.000008142063,0.00006431821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3537028,0.01547103,0.07422983,0.001475837,0.0008925302,0.0003842338,0.0001233527,0.005668376,0.0490525,0.0007509403,0.003062599,0.495186],"study_design_scores_gemma":[0.07538723,0.5836431,0.2899374,0.0002093074,0.00120154,0.001614343,0.0001047829,0.007115885,0.0257116,0.001198117,0.01381738,0.00005935049],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959987,0.001655037,0.0004069328,0.0001075507,0.00007752385,0.0002749162,0.0001053417,0.00002193827,0.001351966],"genre_scores_gemma":[0.9984221,0.0003926542,0.0003482979,0.0001071754,0.00003398252,0.0001335795,0.0000892204,0.000002057209,0.0004708596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002052657,"threshold_uncertainty_score":0.006866872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09291352606650967,"score_gpt":0.519990389511475,"score_spread":0.4270768634449654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}