{"id":"W4406699108","doi":"10.1016/j.ncl.2024.12.013","title":"Experimental Therapeutics in Parkinson’s Disease","year":2025,"lang":"en","type":"review","venue":"Neurologic Clinics","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"Department of Medicine, University of Toronto; National Institutes of Health; Canadian Institutes of Health Research; Parkinson Canada; Ontario Ministry of Health and Long-Term Care; Parkinson Society Canada; Michael J. Fox Foundation for Parkinson's Research; Ministry of Health, Ontario","keywords":"Medicine; Parkinson's disease; Disease; Physical medicine and rehabilitation; Neuroscience; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001776182,0.0005865527,0.00187309,0.0002833527,0.00005543933,0.00002509277,0.00025518,0.0004391174,0.0001260857],"category_scores_gemma":[0.0001407042,0.0004388861,0.0008623098,0.0003514118,0.00006104834,0.00002708902,0.0001685174,0.0006681436,0.0001266978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001619061,"about_ca_system_score_gemma":0.0009408781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002686389,"about_ca_topic_score_gemma":0.000001260154,"domain_scores_codex":[0.9972987,0.0002832649,0.0008003768,0.0009029286,0.0002918083,0.0004229422],"domain_scores_gemma":[0.9981937,0.0003968336,0.0002722703,0.0008233665,0.00002598282,0.0002878331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000306482,0.002385294,0.001652417,0.005953134,0.0001941713,0.003458984,0.00001014263,4.412735e-7,1.507011e-7,0.0001044102,0.0002757451,0.9856586],"study_design_scores_gemma":[0.001228729,0.0004743868,0.0006979696,0.002025796,0.002205597,0.00002029065,0.000003568499,0.0000270411,5.421931e-7,0.000152136,0.992905,0.0002589907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004874133,0.9957191,0.00000329215,0.0001292614,0.0007764265,0.001512374,0.0001467455,0.0001076592,0.001117754],"genre_scores_gemma":[0.001813952,0.9924921,0.00008320183,0.003894743,0.000131719,0.0004412755,0.0002465484,0.00005491299,0.0008415956],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9926292,"threshold_uncertainty_score":0.9998063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1041145616991163,"score_gpt":0.4108805204867053,"score_spread":0.306765958787589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}