{"id":"W4406702493","doi":"10.1093/ecco-jcc/jjae190.1017","title":"P0843 Efficacy by baseline disease characteristics of subcutaneous guselkumab induction therapy in patients with moderately to severely active Crohn’s disease: Results at Week 12 from the phase 3 GRAVITI study","year":2025,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Crohn's disease; Internal medicine; Disease; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001810998,0.0006510849,0.00166268,0.0002444579,0.0002222451,0.0006907604,0.00044001,0.0006674169,0.003132551],"category_scores_gemma":[0.00142635,0.0002108238,0.001419501,0.0004377622,0.0004366094,0.0005372521,0.0004167054,0.001383202,0.0004656567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004074591,"about_ca_system_score_gemma":0.0005313607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003353441,"about_ca_topic_score_gemma":0.0008391077,"domain_scores_codex":[0.9989883,0.0005678938,0.00007087502,0.0001280999,0.0001532037,0.00009165019],"domain_scores_gemma":[0.9986793,0.0003471961,0.0004181264,0.00009101909,0.0001069625,0.0003573721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.766556,0.006751622,0.06927714,0.001123943,0.004000666,0.000152073,0.0001487679,0.0008003337,0.02207705,0.0001241169,0.00384926,0.125139],"study_design_scores_gemma":[0.1742092,0.3339361,0.4768718,0.0001418304,0.003854705,0.0003697848,0.0001096598,0.00163814,0.003597944,0.0003434233,0.00484353,0.00008383403],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990368,0.006111543,0.000255518,0.0003704703,0.00005273556,0.0003288409,0.001153866,0.00005740359,0.001301662],"genre_scores_gemma":[0.9964719,0.0007041946,0.0004752672,0.0003488196,0.0001219083,0.0003052575,0.001069801,0.00001026529,0.0004926281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003132551,"threshold_uncertainty_score":0.01047945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008134514141349105,"score_gpt":0.2473768950849819,"score_spread":0.2392423809436328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}