{"id":"W4406704954","doi":"10.1093/ecco-jcc/jjae190.0088","title":"DOP049 Vedolizumab is more effective at inducing histo-endoscopic healing in early Crohn’s Disease compared to late CD, with comparable healing rates regardless of disease location: data from the LOVE-CD trial","year":2025,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Vedolizumab; Crohn's disease; Wound healing; Disease; Inflammatory bowel disease; Surgery; Dermatology; Gastroenterology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002124028,0.000472505,0.001989568,0.0002265115,0.0002110283,0.0009518157,0.0003935891,0.0007714332,0.002783009],"category_scores_gemma":[0.00158699,0.0002309696,0.001286362,0.0002117828,0.0005673381,0.0007114199,0.0002372852,0.001295795,0.0004040735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000230302,"about_ca_system_score_gemma":0.0002254634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001525485,"about_ca_topic_score_gemma":0.0003944735,"domain_scores_codex":[0.9989237,0.0007295638,0.000094759,0.0001053459,0.00006580191,0.0000807376],"domain_scores_gemma":[0.9980974,0.0008004444,0.0004119934,0.0001252187,0.00009309927,0.0004719632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9430491,0.004051507,0.003976204,0.001410842,0.001781357,0.00006657635,0.00005247987,0.0002406578,0.007432447,0.00008291102,0.0009825802,0.03687324],"study_design_scores_gemma":[0.6311906,0.3242335,0.03442495,0.0002592637,0.002223185,0.0003249769,0.0001063091,0.0007178295,0.003034059,0.000229036,0.003209212,0.00004704295],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802633,0.01639735,0.0002435115,0.0003267787,0.0002146814,0.0002117748,0.0005101699,0.00002487548,0.001807536],"genre_scores_gemma":[0.9944589,0.002788749,0.0003635839,0.0004230121,0.0002521643,0.0001557802,0.0006718335,0.000008062974,0.0008779588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002783009,"threshold_uncertainty_score":0.01123303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01707378721954803,"score_gpt":0.2871508734994022,"score_spread":0.2700770862798542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}