{"id":"W4406722996","doi":"10.1002/mabi.202400464","title":"Investigating How All‐Trans Retinoic Acid Polycaprolactone (atRA‐PCL) Microparticles Alter the Material Properties of 3D Printed Fibrin Constructs","year":2025,"lang":"en","type":"article","venue":"Macromolecular Bioscience","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Victoria","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche sur Alzheimer; British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Pacific Alzheimer Research Foundation; Michael Smith Health Research BC","keywords":"Polycaprolactone; Scaffold; Retinoic acid; Microfluidics; Fibrin; Drug delivery; Tissue engineering; Chemistry; Microparticle; Materials science; Nanotechnology; Biomedical engineering; Biophysics; Chemical engineering; Polymer; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001957956,0.0002110221,0.0001165277,0.000122638,0.0001111324,0.000378635,0.0001103843,0.0002660798,0.0005896352],"category_scores_gemma":[0.0002603065,0.000117027,0.0002174055,0.0001035246,0.0002079862,0.0002601336,0.0001225904,0.0002614367,0.0001971687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002201665,"about_ca_system_score_gemma":0.0001272464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003074952,"about_ca_topic_score_gemma":0.0003976086,"domain_scores_codex":[0.9998834,0.00001360777,0.000011122,0.0000321944,0.00003811196,0.00002158976],"domain_scores_gemma":[0.9998265,0.00006483485,0.00007110129,0.00001413715,0.00001238783,0.00001098119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001539681,0.000007412455,0.00007292084,0.00002220965,0.000002403504,0.00003156751,0.00001279364,0.0001818091,0.9986929,0.00004621113,0.000007289578,0.0009072031],"study_design_scores_gemma":[0.000001260909,0.00003285089,0.0004413715,0.000001152498,0.000002916139,0.00003161256,0.000005795183,0.0004282146,0.9987873,0.000009635219,0.0002560629,0.000001887135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860612,0.001064499,0.01103401,0.00005414341,0.00003167351,0.00003132493,0.0001430423,0.00008381162,0.00149636],"genre_scores_gemma":[0.9884717,0.0007533875,0.009409704,0.00003899142,0.000005401565,0.0000255197,0.00007737484,0.00002317052,0.001194577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005896352,"threshold_uncertainty_score":0.001972556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01570011639009425,"score_gpt":0.242615625299214,"score_spread":0.2269155089091198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}