{"id":"W4406733095","doi":"10.1021/jacs.4c14240","title":"Diving into Unknown Waters: Water-Soluble Clickable Au<sub>13</sub> Nanoclusters Protected with N-Heterocyclic Carbenes for Bio-Medical Applications","year":2025,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Nanocluster Synthesis and Applications","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Queen's University","funders":"Queen's University; Canada Research Chairs; Japan Society for the Promotion of Science; Government of Ontario","keywords":"Chemistry; Nanoclusters; Water soluble; Combinatorial chemistry; Nanotechnology; Environmental chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005639623,0.0002362685,0.0005049825,0.00004149423,0.0005024854,0.0001212688,0.001093734,0.0001064421,0.000009958437],"category_scores_gemma":[0.00008402774,0.0001270299,0.0004425728,0.0004546639,0.0007421992,0.0001554022,0.0003479726,0.0002918931,0.000006370166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003452447,"about_ca_system_score_gemma":0.000251678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001497032,"about_ca_topic_score_gemma":0.00002778506,"domain_scores_codex":[0.9979317,0.00007699097,0.0006375104,0.0003454012,0.0004990489,0.0005093193],"domain_scores_gemma":[0.9983165,0.0002554357,0.0005432477,0.0004623554,0.0002348431,0.000187621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006766765,0.0001413382,0.0004491862,0.00008602584,0.00008287054,2.867789e-7,0.0004394982,0.00003561799,0.9923175,0.00002838454,0.001561597,0.004790019],"study_design_scores_gemma":[0.0005457763,0.00006867176,0.000127032,0.0001812834,0.0001184335,0.00002104552,0.0004294792,0.0002561257,0.9872363,0.0003430863,0.01048962,0.0001831852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607913,0.00004832989,0.02932196,0.008947983,0.0001524652,0.0006556509,0.00000747259,0.00004350334,0.00003136943],"genre_scores_gemma":[0.9908211,0.00003176775,0.007231284,0.001128939,0.0002756011,0.000396414,0.000003782093,0.00002787683,0.00008318295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03002988,"threshold_uncertainty_score":0.5180128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006281272083243635,"score_gpt":0.2415074970800007,"score_spread":0.2352262249967571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}