{"id":"W4406734951","doi":"10.1007/s11886-025-02202-1","title":"The Accuracy of Technetium-99 m Pyrophosphate Imaging in Diagnosing Transthyretin Cardiac Amyloidosis and Its Impact on Patient Management","year":2025,"lang":"en","type":"review","venue":"Current Cardiology Reports","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary General Hospital; Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"","keywords":"Medicine; Transthyretin; Single-photon emission computed tomography; Diagnostic accuracy; Cardiac amyloidosis; Pyrophosphate; Nuclear medicine; Radiology; Internal medicine; Nuclear magnetic resonance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002470945,0.0007627509,0.002371471,0.001979578,0.0001463308,0.001447491,0.001127385,0.001254701,0.001125571],"category_scores_gemma":[0.004641571,0.0003052581,0.0007167694,0.001509783,0.0006183129,0.0009153921,0.0004208058,0.002153588,0.0006837031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005822834,"about_ca_system_score_gemma":0.001172789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001103576,"about_ca_topic_score_gemma":0.001555008,"domain_scores_codex":[0.9992821,0.0001643636,0.0001303313,0.0001321986,0.0002532714,0.00003782966],"domain_scores_gemma":[0.9959061,0.002970788,0.0003656164,0.0000623194,0.0005997021,0.00009544017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001802318,0.00004571324,0.001965009,0.008591427,0.0004089711,0.0003360407,0.00003055497,0.000342075,0.0008591464,0.001127059,0.01059178,0.975522],"study_design_scores_gemma":[0.0003674049,0.0007262923,0.0324938,0.03338345,0.004508403,0.0194394,0.0003243979,0.001484745,0.002993406,0.0087475,0.8952932,0.0002379699],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001627791,0.999089,0.0001174159,0.0002725361,0.0001020557,0.000001357272,0.0000117159,0.000002770553,0.0002403075],"genre_scores_gemma":[0.00219471,0.9967147,0.000298609,0.0002885032,0.000353748,0.000003635417,0.00003143956,0.000002095068,0.0001125286],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002470945,"threshold_uncertainty_score":0.01306772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011982372505679,"score_gpt":0.3338849223167443,"score_spread":0.3219025498110653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}