{"id":"W4406765211","doi":"10.1177/20417314241284826","title":"Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization","year":2025,"lang":"en","type":"article","venue":"Journal of Tissue Engineering","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Stem Cell Network","keywords":"Transplantation; Oxygenation; Islet; Artificial pancreas; Immunosuppression; Medicine; Perfusion; Biomedical engineering; Insulin; Chemistry; Type 1 diabetes; Internal medicine; Diabetes mellitus; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004059119,0.0003270242,0.0001447435,0.0002760484,0.0001402594,0.0003947917,0.000187452,0.0003055228,0.0006978465],"category_scores_gemma":[0.0003134628,0.00009539336,0.0002269247,0.0001595828,0.0001847002,0.0002698064,0.0001961176,0.0003138147,0.000141696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002370044,"about_ca_system_score_gemma":0.0001743479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003093457,"about_ca_topic_score_gemma":0.0004038721,"domain_scores_codex":[0.9998629,0.0000177126,0.000009898443,0.00002882088,0.000057032,0.00002367465],"domain_scores_gemma":[0.999836,0.00004300027,0.00005266187,0.0000135924,0.00002902704,0.00002566302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006658784,0.00003561401,0.0003103403,0.00007293581,0.000004345531,0.00005011854,0.00004055194,0.001796618,0.9924514,0.0002020771,0.00004613118,0.004923208],"study_design_scores_gemma":[0.000008726608,0.0005827017,0.002830704,0.00001832637,0.00002368519,0.0001134872,0.00003223285,0.005605154,0.9869321,0.0001054852,0.003736537,0.0000109609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722942,0.001600663,0.02329359,0.00007586284,0.00003948397,0.00006175693,0.0002674424,0.0001528767,0.002214121],"genre_scores_gemma":[0.9862017,0.001073982,0.01123421,0.0000287021,0.000008603865,0.00009936558,0.0002574407,0.00002919379,0.00106675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006978465,"threshold_uncertainty_score":0.002334535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555685167196286,"score_gpt":0.290076667526582,"score_spread":0.2745198158546192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}