{"id":"W4406795493","doi":"10.2196/71293","title":"Peer Review of “Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy for Recurrent Glioblastoma: An Augmented Meta-Analysis of Phase 1 Clinical Trials (Preprint)”","year":2025,"lang":"en","type":"article","venue":"JMIRx Med","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Preprint; Chimeric antigen receptor; Meta-analysis; Glioblastoma; Medicine; Clinical trial; Oncology; Internal medicine; Cancer research; Immunotherapy; Computer science; Cancer; World Wide Web","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01876727,0.0002369508,0.004605233,0.00050766,0.00003208667,0.000006142046,0.0002517502,0.0001370413,0.005376581],"category_scores_gemma":[0.005354453,0.000150803,0.002626971,0.001470516,0.0002164824,0.00004010214,0.00005766662,0.0002289245,0.000001624826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003375675,"about_ca_system_score_gemma":0.0002978916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002579982,"about_ca_topic_score_gemma":0.000009505771,"domain_scores_codex":[0.9937575,0.001810537,0.002750128,0.0005486632,0.0008996635,0.0002335284],"domain_scores_gemma":[0.9931476,0.002940844,0.001087717,0.001053125,0.001583209,0.0001874836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.08618722,0.01221475,0.0005916242,0.005250854,0.1765577,0.000001944614,0.0005780926,0.000004626339,0.3204787,0.0000551163,0.0148989,0.3831805],"study_design_scores_gemma":[0.05618471,0.01649152,0.003557599,0.001157341,0.1650486,0.000001484175,0.0001861367,0.0009397123,0.3350163,0.00002498806,0.4209885,0.000403093],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8712869,0.09190796,0.001283816,0.01558655,0.0003857462,0.01724578,0.0008370077,0.00006374721,0.001402447],"genre_scores_gemma":[0.497622,0.414439,0.007027174,0.001717534,0.0003894616,0.001237332,0.001725884,0.0001915497,0.07565013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4060896,"threshold_uncertainty_score":0.9955326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2552106420503055,"score_gpt":0.540461303106882,"score_spread":0.2852506610565765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}