{"id":"W4406808042","doi":"10.2147/dddt.s504485","title":"Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation","year":2025,"lang":"en","type":"article","venue":"Drug Design Development and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Psoriasis; Keratinocyte; Inflammation; Medicine; Dermatology; Immunology; Biology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008711078,0.0003622672,0.0002864715,0.0002423684,0.00008782542,0.0001777629,0.000135592,0.0001176455,0.001553004],"category_scores_gemma":[0.00006945836,0.00009500844,0.0003003608,0.0001268501,0.0001831157,0.0001643412,0.0001112752,0.0006596288,0.000260419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001057802,"about_ca_system_score_gemma":0.0002086512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002567503,"about_ca_topic_score_gemma":0.0006161301,"domain_scores_codex":[0.9999483,0.000008083409,0.000004488226,0.000008763518,0.0000151232,0.000015237],"domain_scores_gemma":[0.9999584,0.000004428872,0.00001175482,0.000003737046,0.000008301601,0.00001333431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006811634,0.0002536709,0.0003655766,0.0004393507,0.00002640515,0.00006567714,0.00001757322,0.0001277569,0.9845628,0.00009072587,0.0002444096,0.01312483],"study_design_scores_gemma":[0.0006381465,0.008044161,0.0198855,0.0001161902,0.0002634439,0.0007447132,0.0001506822,0.00149079,0.9499053,0.0003650489,0.01837371,0.00002233018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734383,0.01618138,0.003494994,0.0002029974,0.0002527503,0.0001612412,0.0005439186,0.000338822,0.005385647],"genre_scores_gemma":[0.9857185,0.00908079,0.00175757,0.0001647776,0.00004617718,0.00006327481,0.0004648109,0.00002829582,0.002675767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001553004,"threshold_uncertainty_score":0.00519532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01499987061481366,"score_gpt":0.2226122192564066,"score_spread":0.207612348641593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}