{"id":"W4406811164","doi":"10.1371/journal.pone.0316672","title":"Evidence of a persistent altered neural state in people with fibromyalgia syndrome during functional MRI studies and its relationship with pain and anxiety","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Functional magnetic resonance imaging; Fibromyalgia; Anxiety; Resting state fMRI; Neuroscience; Psychology; Pupillary response; Audiology; Medicine; Physical medicine and rehabilitation; Psychiatry; Pupil","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003447708,0.0002280714,0.0002242823,0.000768189,0.0002278816,0.0002829403,0.0001279081,0.0004143311,0.0007826948],"category_scores_gemma":[0.001417369,0.0001233165,0.0001522037,0.0002788124,0.0003132746,0.0002731619,0.0002851583,0.0002297309,0.00009137211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001119603,"about_ca_system_score_gemma":0.00007458382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005878805,"about_ca_topic_score_gemma":0.00138906,"domain_scores_codex":[0.9998108,0.00004593287,0.00002273721,0.00004203452,0.00004392478,0.00003454775],"domain_scores_gemma":[0.9993605,0.0001412714,0.0003403041,0.00003603407,0.00004545114,0.00007630312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001045431,0.0001473596,0.8931882,0.0001319022,0.0001371357,0.002567425,0.001951105,0.000103165,0.083648,0.00008393526,0.0001292751,0.01686706],"study_design_scores_gemma":[0.000003513091,0.0001432702,0.99748,0.000003416826,0.0000120221,0.001477699,0.0002353316,0.00007629861,0.0004791825,0.00003301325,0.00005310601,0.000003144742],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993334,0.0001440383,0.0001840765,0.00002602073,0.000002139714,0.00000506756,0.00003273338,0.000003776767,0.0002685917],"genre_scores_gemma":[0.99963,0.00005877877,0.0001960333,0.00001669612,0.000009410066,0.000005006626,0.00004069786,7.205235e-7,0.00004262086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007826948,"threshold_uncertainty_score":0.002618372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07264849722919837,"score_gpt":0.2791163266716171,"score_spread":0.2064678294424188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}