{"id":"W4406815113","doi":"10.1002/cam4.70369","title":"Patterns of Treatment and Real‐World Outcomes of Patients With Non‐small Cell Lung Cancer With <scp><i>EGFR</i></scp> Exon 20 Insertion Mutations Receiving Mobocertinib: The <scp>EXTRACT</scp> Study","year":2025,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"William Osler Health System; University of Toronto; Princess Margaret Cancer Centre","funders":"Takeda Development Center Americas","keywords":"Medicine; Internal medicine; Lung cancer; Cohort; Demographics; Adverse effect; Oncology; Demography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001488029,0.000396939,0.0008314569,0.0003192661,0.0001807737,0.00001319928,0.0001243995,0.00006398049,0.00003330174],"category_scores_gemma":[0.00007627755,0.000207965,0.00006555229,0.0006783811,0.0001705875,0.0001121527,0.00003406339,0.0001800789,4.097657e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006465924,"about_ca_system_score_gemma":0.0007072461,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01532159,"about_ca_topic_score_gemma":0.01927216,"domain_scores_codex":[0.9980629,0.00007338879,0.0006319813,0.0004854444,0.0003988344,0.0003474591],"domain_scores_gemma":[0.9976822,0.0006260567,0.0005332623,0.0004954502,0.0005000306,0.0001629648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006952084,0.0009759996,0.9776859,0.000418577,0.001446321,0.000008380045,0.014594,0.0002886881,0.0004044981,0.00001006585,0.0006475386,0.003450474],"study_design_scores_gemma":[0.01265836,0.002435201,0.9670538,0.001444332,0.005007571,0.000001028783,0.008721668,0.00009908311,0.001535503,0.00000576404,0.0009871303,0.00005055647],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909657,0.001870576,0.0001778901,0.0007860555,0.0002596148,0.002916265,0.0001761387,0.00004108244,0.002806725],"genre_scores_gemma":[0.9899954,0.0009877927,0.0000992999,0.0003708542,0.00009224866,0.001091524,0.0001387673,0.00004962698,0.007174455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01258884,"threshold_uncertainty_score":0.9986235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391007575968486,"score_gpt":0.3151120880114066,"score_spread":0.3012020122517217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}