{"id":"W4406815113","doi":"10.1002/cam4.70369","title":"Patterns of Treatment and Real‐World Outcomes of Patients With Non‐small Cell Lung Cancer With <scp><i>EGFR</i></scp> Exon 20 Insertion Mutations Receiving Mobocertinib: The <scp>EXTRACT</scp> Study","year":2025,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"William Osler Health System; University of Toronto; Princess Margaret Cancer Centre","funders":"Takeda Development Center Americas","keywords":"Medicine; Internal medicine; Lung cancer; Cohort; Demographics; Adverse effect; Oncology; Demography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000916646,0.0001598287,0.0003495589,0.000537333,0.0002982228,0.000786128,0.0003415789,0.0003162867,0.001065866],"category_scores_gemma":[0.002425787,0.0001411491,0.0005380507,0.001155797,0.0002644811,0.0005753518,0.0005163323,0.0004622018,0.000201653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008449998,"about_ca_system_score_gemma":0.0008132809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005625459,"about_ca_topic_score_gemma":0.009239008,"domain_scores_codex":[0.9990461,0.0002045104,0.0001782096,0.000244286,0.0001643408,0.0001624943],"domain_scores_gemma":[0.9961726,0.0003795263,0.002582935,0.0001529555,0.0003115294,0.0004005571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000228156,0.00002579617,0.9983859,0.00001372352,0.00006682337,0.0000299406,0.00004019462,0.00004473888,0.00005584985,0.000009433753,0.0001535958,0.0009456886],"study_design_scores_gemma":[0.00002251194,0.0001958467,0.9988925,0.00001042731,0.00003735258,0.0001554941,0.0001789989,0.0001509054,0.00004993492,0.00001717609,0.0002833113,0.000005629343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997683,0.0002742596,0.00004503935,0.00005698233,0.000004290528,0.00002108583,0.001442101,0.000003090116,0.0004701964],"genre_scores_gemma":[0.998549,0.00008392201,0.00003133396,0.0000310188,0.000004702857,0.00001697608,0.001203811,0.000001617252,0.0000774924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005625459,"threshold_uncertainty_score":0.01118541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391007575968486,"score_gpt":0.3151120880114066,"score_spread":0.3012020122517217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}