{"id":"W4406837213","doi":"10.36838/v6i11.8","title":"Epigenetic Pathways in Breast Cancer: Diagnostic Markers, Transgenerational Impacts, and Emerging Therapies","year":2024,"lang":"en","type":"article","venue":"International journal of high school research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Transgenerational epigenetics; Epigenetics; Breast cancer; Cancer; Medicine; Computational biology; Biology; Bioinformatics; Genetics; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001171028,0.0000956578,0.0001040759,0.0003863188,0.00004907899,0.0001837834,0.0002369157,0.00007867409,0.0001592559],"category_scores_gemma":[0.0003004373,0.00008162236,0.00006049796,0.0001447805,0.00007089204,0.00002275488,0.00005919422,0.0003015953,0.000003778975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008413659,"about_ca_system_score_gemma":0.0004147075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000125143,"about_ca_topic_score_gemma":0.0001054386,"domain_scores_codex":[0.9984766,0.0001705922,0.0003353421,0.0001900839,0.0006324623,0.0001948788],"domain_scores_gemma":[0.9990176,0.0001910275,0.0000524029,0.00008026901,0.0005353517,0.0001233525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004338729,0.0001024814,0.07958875,0.00004893676,0.0004180432,0.0001883439,0.0002711985,0.001812614,0.8462783,0.0009100483,0.001660949,0.06828648],"study_design_scores_gemma":[0.001624783,0.0005492506,0.8729988,0.0007035164,0.00002744445,0.0002329594,0.0002962623,0.001105503,0.09864141,0.008194779,0.01529169,0.0003336409],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.94353,0.05038165,0.0008315694,0.004541047,0.0005024989,0.00008142787,0.00006663276,0.000002615152,0.00006252536],"genre_scores_gemma":[0.9464809,0.05207787,0.0003128058,0.00003947016,0.000974578,0.00001105753,0.00002209865,0.00001645328,0.0000647102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.79341,"threshold_uncertainty_score":0.3328463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02304457827955095,"score_gpt":0.3562237718278258,"score_spread":0.3331791935482748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}