{"id":"W4406845031","doi":"10.1038/s43587-025-00807-3","title":"Transposable element methylation tracks age","year":2025,"lang":"en","type":"article","venue":"Nature Aging","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cargill (Canada)","funders":"Hungarian Science Foundation","keywords":"Transposable element; Element (criminal law); Methylation; DNA Transposable Elements; DNA methylation; Biology; Genetics; Computational biology; Evolutionary biology; Genome; Political science; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002579644,0.0001892609,0.0001913464,0.0004252438,0.0001569202,0.0005979924,0.0001861139,0.0004207069,0.00344348],"category_scores_gemma":[0.0004467858,0.0001576675,0.0001844309,0.0003004198,0.0002094876,0.0004337539,0.000219217,0.0003746327,0.0009391861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003676717,"about_ca_system_score_gemma":0.0002239587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001553083,"about_ca_topic_score_gemma":0.002532871,"domain_scores_codex":[0.9999036,0.000008703501,0.000004872459,0.00003840564,0.00002590525,0.00001854277],"domain_scores_gemma":[0.9997581,0.00002945144,0.000087206,0.00002876673,0.0000587152,0.00003767673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005096255,0.00004196828,0.03387709,0.00009822245,0.00008168439,0.0001611843,0.0002306253,0.0003290173,0.9224807,0.004148709,0.00203836,0.03600284],"study_design_scores_gemma":[0.00003619468,0.0007432792,0.4727855,0.00005559834,0.0001964869,0.001249088,0.0004895163,0.003734838,0.4426967,0.008872516,0.06908071,0.00005956594],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9576669,0.01525917,0.01120158,0.001505782,0.0004463899,0.00002704559,0.003886024,0.0004790444,0.009528004],"genre_scores_gemma":[0.9830121,0.00344626,0.001678219,0.0002974052,0.00007239847,0.00001087904,0.0007716304,0.00004908331,0.01066192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00344348,"threshold_uncertainty_score":0.01151961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004814815802292468,"score_gpt":0.2871224225153279,"score_spread":0.2823076067130354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}