{"id":"W4406859276","doi":"10.20944/preprints202501.1962.v1","title":"Spatial Gene Expression of Human Coronary Arteries Revealed the Molecular Features of Diffuse Intimal Thickening in Explanted Hearts","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Providence Health Care; Heart and Stroke Foundation of Canada","keywords":"Thickening; Coronary arteries; Anatomy; Artery; Cardiology; Pathology; Medicine; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238571,0.0002095795,0.0001787607,0.0002661095,0.0001577599,0.0002413368,0.00009771298,0.0002217576,0.001458776],"category_scores_gemma":[0.0002486193,0.0001577196,0.000247276,0.0002401476,0.0002407441,0.00008247348,0.0001674508,0.0004335081,0.0005828969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001100626,"about_ca_system_score_gemma":0.0001430797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004799339,"about_ca_topic_score_gemma":0.0006818768,"domain_scores_codex":[0.9997823,0.00001737387,0.00001081787,0.0001046512,0.00005143145,0.00003342603],"domain_scores_gemma":[0.9999049,0.00003069922,0.00001267114,0.00001769463,0.00002266565,0.00001148259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001014972,0.00001050954,0.0009383688,0.00002708992,0.000006535472,0.00005780841,0.00005698441,0.00007067774,0.9968911,0.00005239897,0.00006400285,0.001723147],"study_design_scores_gemma":[0.00002172236,0.0005210937,0.1032919,0.00003290151,0.00008555598,0.0006630535,0.0002515225,0.002233488,0.887557,0.0002281192,0.005100679,0.00001303233],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794887,0.001377394,0.01292941,0.00008543357,0.00008686871,0.00003997445,0.003370017,0.0001255207,0.002496595],"genre_scores_gemma":[0.9679142,0.001207734,0.01647669,0.0001736562,0.00004211788,0.0001229896,0.008202015,0.0001402771,0.005720256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458776,"threshold_uncertainty_score":0.004880071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04948326438106408,"score_gpt":0.3208025516141328,"score_spread":0.2713192872330688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}