{"id":"W4406859473","doi":"10.20944/preprints202501.2034.v1","title":"Mini Review: Gut Microbiome &amp; Early Detection of Colorectal Cancer","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gut microbiome; Colorectal cancer; Microbiome; Medicine; Internal medicine; Computational biology; Biology; Cancer; Bioinformatics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001253417,0.001085976,0.001881429,0.002547677,0.000583814,0.003140721,0.001282717,0.002832172,0.02416454],"category_scores_gemma":[0.004221493,0.0004151976,0.001207914,0.002528877,0.0007144613,0.002676871,0.001481298,0.002480044,0.01232961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001091661,"about_ca_system_score_gemma":0.002770615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007925806,"about_ca_topic_score_gemma":0.001092857,"domain_scores_codex":[0.9991172,0.0002139802,0.0001017259,0.0001605266,0.0003215546,0.00008504972],"domain_scores_gemma":[0.9969993,0.00117705,0.0003963988,0.00008330319,0.0009611419,0.0003829082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000233368,0.00005747348,0.000409292,0.03424935,0.0002883986,0.0002472899,0.0001466125,0.000158562,0.001404978,0.002586117,0.5700459,0.3901727],"study_design_scores_gemma":[0.00001648517,0.00006011089,0.001076083,0.004865717,0.0001737292,0.0005963156,0.0000839399,0.00004947318,0.0003642506,0.00143527,0.991256,0.00002271968],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002763105,0.9592491,0.0003693414,0.008723526,0.027717,0.00003553722,0.0004141662,0.0001140155,0.003101007],"genre_scores_gemma":[0.001534628,0.9609926,0.0004821684,0.004483307,0.02466069,0.00005386645,0.0007330599,0.00006862796,0.006991135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02416454,"threshold_uncertainty_score":0.08083838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05600140411621844,"score_gpt":0.3643413995828639,"score_spread":0.3083399954666455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}