{"id":"W4406860729","doi":"10.1101/2025.01.25.634869","title":"Decoy-seq unlocks scalable genetic screening for regulatory small noncoding RNAs","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Genome Canada","funders":"","keywords":"Computational biology; Decoy; Biology; Long non-coding RNA; Genetics; Computer science; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009609203,0.0005468401,0.0008462105,0.0004709898,0.0003358105,0.0007912514,0.0006952722,0.0007235435,0.001779909],"category_scores_gemma":[0.0009130681,0.0003793475,0.0004598439,0.0002250236,0.0005243184,0.0004429887,0.001142765,0.001138714,0.001021167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005105102,"about_ca_system_score_gemma":0.0005082587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006224511,"about_ca_topic_score_gemma":0.001692092,"domain_scores_codex":[0.9988493,0.0001121293,0.00006067126,0.0004169503,0.0004621539,0.00009874796],"domain_scores_gemma":[0.999316,0.0002306303,0.0001110251,0.0001328421,0.0001169717,0.00009250978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006558366,0.00002807857,0.000331458,0.00005878405,0.00001272669,0.00003287824,0.0000182547,0.0007389602,0.9917631,0.0003399557,0.0004029873,0.006207114],"study_design_scores_gemma":[0.00001780881,0.0001498185,0.0008896169,0.000007522223,0.00001101638,0.00007736592,0.00002125087,0.02219125,0.9724169,0.0003035673,0.003888146,0.00002564789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4654992,0.001466507,0.5074123,0.0005734573,0.0002937059,0.000688176,0.005904484,0.01314579,0.005016375],"genre_scores_gemma":[0.7298061,0.0009719376,0.2510316,0.001088363,0.00007731411,0.00110059,0.006264074,0.001517946,0.008142055],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001779909,"threshold_uncertainty_score":0.005954385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996599954028246,"score_gpt":0.2528052427733134,"score_spread":0.2328392432330309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}