{"id":"W4406883988","doi":"10.1097/tp.0000000000005332","title":"Donor-derived Cell-free DNA: A Step Forward in the Quest for Transplant Truth","year":2025,"lang":"en","type":"article","venue":"Transplantation","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Cell-free fetal DNA; DNA; Medicine; Chemistry; Biology; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01481391,0.0004088127,0.001394325,0.00110434,0.0009726922,0.005248273,0.001663738,0.006159571,0.016181],"category_scores_gemma":[0.01463187,0.0003467729,0.0006428956,0.0006443601,0.007163355,0.00847034,0.002449523,0.01194801,0.00502959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002294196,"about_ca_system_score_gemma":0.003052431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005736456,"about_ca_topic_score_gemma":0.0007316013,"domain_scores_codex":[0.9979153,0.0007906194,0.000127683,0.0002668383,0.0007386819,0.0001609109],"domain_scores_gemma":[0.9831956,0.01192506,0.0006933921,0.001246899,0.001604035,0.001335031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001349716,0.0005960562,0.002894376,0.002377359,0.0001145409,0.0009398142,0.0008393177,0.0009527878,0.02369471,0.3319582,0.1399788,0.4943044],"study_design_scores_gemma":[0.0002649053,0.0008836365,0.001234081,0.001155937,0.00008965301,0.003211107,0.0007731224,0.000968057,0.01370647,0.2516582,0.725966,0.00008871372],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01192534,0.4162623,0.08445708,0.4451129,0.01898075,0.0001192831,0.0006732509,0.000642331,0.02182682],"genre_scores_gemma":[0.2253267,0.4269306,0.08908284,0.1939034,0.03520345,0.0003192289,0.001246739,0.0007831428,0.02720399],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.016181,"threshold_uncertainty_score":0.07834435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006735969572058837,"score_gpt":0.2393806267043935,"score_spread":0.2326446571323347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}