{"id":"W4406886085","doi":"10.1007/s12028-024-02207-8","title":"Description of STRIVE-ON Study Protocol: Safety and Tolerability of GTX-104 (Nimodipine Injection for IV Infusion) Compared with Oral Nimodipine in Patients Hospitalized for Aneurysmal Subarachnoid Hemorrhage (aSAH): A Prospective, Randomized, Phase III Trial (STRIVE-ON)","year":2025,"lang":"en","type":"article","venue":"Neurocritical Care","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Nimodipine; Medicine; Tolerability; Anesthesia; Subarachnoid hemorrhage; Dosing; Adverse effect; Pharmacology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002236901,0.0003351807,0.001295177,0.0002578992,0.0001598847,0.00002235292,0.0001029113,0.000108371,0.00001019574],"category_scores_gemma":[0.0007735475,0.0002566228,0.0001990158,0.0004206934,0.000262142,0.0001211483,0.00004378525,0.0002347198,2.696864e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000155226,"about_ca_system_score_gemma":0.0001299847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006446229,"about_ca_topic_score_gemma":0.00003737651,"domain_scores_codex":[0.9975252,0.0002072447,0.0009860626,0.0006350435,0.0003568251,0.000289614],"domain_scores_gemma":[0.9979527,0.0003542046,0.0001908237,0.0003626275,0.001039824,0.0000998431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9452772,0.01184336,0.03723738,0.00110945,0.0000415611,0.000008015117,0.0002913816,0.00002209116,0.0003158143,0.001067606,0.000006671472,0.002779486],"study_design_scores_gemma":[0.8366006,0.0586289,0.099962,0.00009704292,0.0006009746,0.000004761054,0.0003606837,0.001865079,0.001383189,0.0003029459,0.000007012462,0.0001868004],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8488734,0.000004379313,0.001336809,0.0001914495,0.00008035522,0.1490775,0.0002252015,0.00004513755,0.0001657831],"genre_scores_gemma":[0.9492212,2.806867e-7,0.0004904227,0.00007966389,0.00004672304,0.04989598,0.0002109888,0.00002401628,0.00003072336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1086766,"threshold_uncertainty_score":0.9999886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01724523417558429,"score_gpt":0.3132052643375045,"score_spread":0.2959600301619202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}