{"id":"W4406896712","doi":"10.1002/advs.202404697","title":"Aspartate Metabolism‐Driven Gut Microbiota Dynamics and RIP‐Dependent Mitochondrial Function Counteract Oxidative Stress","year":2025,"lang":"en","type":"article","venue":"Advanced Science","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Natural Science Foundation of China","keywords":"Oxidative stress; Gut flora; Reactive oxygen species; Antioxidant; Mitochondrion; Oxidative phosphorylation; Cell biology; Biology; Metabolism; Biochemistry; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002235962,0.0003580294,0.0003618602,0.0002103415,0.0001706144,0.0004538656,0.0001950049,0.0003576414,0.00108842],"category_scores_gemma":[0.0002257387,0.0001170052,0.0002566154,0.0001303242,0.0003142668,0.0003755961,0.0005890802,0.0007569614,0.0002413117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002445371,"about_ca_system_score_gemma":0.0003386343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002367016,"about_ca_topic_score_gemma":0.0005247454,"domain_scores_codex":[0.9998456,0.00003706869,0.00001436252,0.00003602984,0.00002824842,0.00003853436],"domain_scores_gemma":[0.9998686,0.000007089895,0.00004385265,0.00001261476,0.00002530056,0.0000424953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006491172,0.00005344785,0.0006655053,0.0001621417,0.00001498212,0.00005280663,0.00002627084,0.00007110193,0.9914607,0.0001802309,0.0001180354,0.00654559],"study_design_scores_gemma":[0.0001802826,0.002232551,0.03267669,0.00007100452,0.000114945,0.0004862078,0.0003303506,0.002963038,0.9462826,0.001032274,0.0136026,0.00002753694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979155,0.00836119,0.008887699,0.0005722067,0.0001281007,0.0000783471,0.0003840187,0.000187755,0.002245655],"genre_scores_gemma":[0.991789,0.002564471,0.003399143,0.0001519082,0.00002938042,0.00005326351,0.0002818626,0.00002183122,0.001709112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108842,"threshold_uncertainty_score":0.003641069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003864816704000979,"score_gpt":0.267389994478498,"score_spread":0.263525177774497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}