{"id":"W4406901829","doi":"10.1007/s40291-024-00768-0","title":"Molecular Therapeutics in Development to Treat Hyperlipoproteinemia","year":2025,"lang":"en","type":"review","venue":"Molecular Diagnosis & Therapy","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Academic Medical Organization of Southwestern Ontario; Heart and Stroke Foundation of Canada","keywords":"Molecular medicine; Medicine; Human genetics; Pharmacology; Intensive care medicine; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005392133,0.0005700138,0.0005062524,0.0006476627,0.0002835377,0.0009431617,0.0004047605,0.0009397629,0.007584595],"category_scores_gemma":[0.0003802586,0.0001947491,0.0004304588,0.0003546843,0.0003259071,0.0006515246,0.0005725367,0.002534407,0.003646351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004549684,"about_ca_system_score_gemma":0.0006628279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003790435,"about_ca_topic_score_gemma":0.0007890685,"domain_scores_codex":[0.999811,0.00003934607,0.00001409469,0.00002286281,0.00007271247,0.00004005681],"domain_scores_gemma":[0.9998654,0.00001638667,0.00002818383,0.00000949586,0.00004067636,0.00003985637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001278243,0.001325097,0.0008640102,0.0027649,0.0001628078,0.0008395637,0.0001628345,0.0008354367,0.1415916,0.01921517,0.0484259,0.7825345],"study_design_scores_gemma":[0.001543026,0.003572553,0.00221884,0.0006603739,0.0001277229,0.001856268,0.00006516957,0.0007123487,0.03856216,0.00496006,0.9456787,0.00004272722],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05350045,0.7563305,0.03780663,0.02123503,0.006474538,0.00160789,0.002408329,0.002059519,0.1185772],"genre_scores_gemma":[0.2372297,0.6027125,0.04139073,0.01623791,0.002284589,0.001900421,0.005566291,0.0001917832,0.09248599],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007584595,"threshold_uncertainty_score":0.02537304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03964586472466181,"score_gpt":0.3430746492664283,"score_spread":0.3034287845417665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}