{"id":"W4406923587","doi":"10.1021/acs.jnatprod.4c01051","title":"Fatuamide A, a Hybrid PKS/NRPS Metallophore from a <i>Leptolyngbya</i> sp. Marine Cyanobacterium Collected in American Samoa","year":2025,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Department of Environment and Conservation","funders":"National Center for Complementary and Integrative Health; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; University of California, San Diego; Deutsche Forschungsgemeinschaft","keywords":"Cyanobacteria; Stereochemistry; Biology; Chemistry; Botany; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005043008,0.0004036502,0.001296421,0.0007377587,0.0000813077,0.00007685213,0.0003849712,0.0001017254,0.0001245786],"category_scores_gemma":[0.002542789,0.000278834,0.0002825265,0.002222304,0.0002081416,0.0002815896,0.0001989034,0.001382813,0.00001339756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003515843,"about_ca_system_score_gemma":0.0006026495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005473438,"about_ca_topic_score_gemma":0.0001427815,"domain_scores_codex":[0.9971623,0.0001685373,0.001111164,0.0005696609,0.0004879654,0.0005003845],"domain_scores_gemma":[0.9975299,0.0001580672,0.0007022546,0.000497749,0.000958915,0.0001531024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003001995,0.0003678257,0.003692719,0.0001364473,0.000458809,0.0005900346,0.00007716611,0.000001381173,0.9293199,0.00001201394,0.03787942,0.02446228],"study_design_scores_gemma":[0.002925437,0.0004911834,0.1261196,0.0006326399,0.0004831362,0.0005876493,0.00009607757,0.00003753497,0.8024457,0.0002309669,0.06559353,0.0003566051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9603817,0.003854139,0.00000246754,0.03303595,0.001542222,0.0005495616,0.00002925539,0.00003594948,0.0005687419],"genre_scores_gemma":[0.986474,0.0006989386,0.005451934,0.002404907,0.0009673047,0.000001047983,0.00005284248,0.00003250105,0.003916515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1268742,"threshold_uncertainty_score":0.9999664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006032194361908072,"score_gpt":0.2353533152548074,"score_spread":0.2293211208928994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}