{"id":"W4406929096","doi":"10.1038/s41585-024-00993-6","title":"Hallmark discoveries in the biology of non-Wilms tumour childhood kidney cancers","year":2025,"lang":"en","type":"review","venue":"Nature Reviews Urology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Wilms tumour; Wilms' tumor; Kidney cancer; Kidney; Oncology; Pathology; Cancer research; Internal medicine; Kidney disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006709728,0.0005739344,0.002230323,0.0001922996,0.00005426136,0.000009800161,0.001092064,0.002283467,0.00002540083],"category_scores_gemma":[0.0006162089,0.0003119791,0.0009264307,0.0005961102,0.0002833162,0.00000316774,0.0002016433,0.001705703,0.00000914284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005220434,"about_ca_system_score_gemma":0.001443404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004636758,"about_ca_topic_score_gemma":0.00007486416,"domain_scores_codex":[0.99681,0.000936766,0.0009793524,0.0007290592,0.0001081206,0.0004367381],"domain_scores_gemma":[0.9983274,0.0001108701,0.0006833417,0.0007588426,0.00004652912,0.00007298657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004223414,0.00008290668,0.00003192205,0.01761095,0.0004762214,0.00001428056,0.00005462052,0.000005530318,0.0001257991,0.0005513033,0.03534682,0.9456574],"study_design_scores_gemma":[0.0002307421,0.000236749,0.00001041523,0.004369827,0.000553788,0.00007834219,0.000004961407,2.841706e-7,0.00002769699,0.00005976177,0.9941472,0.0002802188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000100186,0.9928184,0.00002330584,0.0003860089,0.0008949304,0.001348824,0.0001656938,0.000004430508,0.004348371],"genre_scores_gemma":[0.000190432,0.9954124,0.0000538486,0.002411389,0.0003603104,0.0003479903,0.0009037026,0.00003024545,0.000289676],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9588004,"threshold_uncertainty_score":0.9999332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00664398306348513,"score_gpt":0.3083711418437416,"score_spread":0.3017271587802565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}