{"id":"W4406964300","doi":"10.31579/2640-1053/214","title":"Genetically Engineered Mouse Model in Preclinical Anti-cancer Drug improvement","year":2024,"lang":"en","type":"article","venue":"Cancer Research and Cellular Therapeutics","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Karachi; University of Calgary","keywords":"Genetically engineered; Drug; Cancer; Cancer drugs; Medicine; Pharmacology; Computational biology; Cancer research; Biology; Internal medicine; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001893661,0.001310916,0.0007922424,0.002171145,0.0005921145,0.001113686,0.001150509,0.001365546,0.007557935],"category_scores_gemma":[0.0006523109,0.0005594959,0.001088492,0.0008159365,0.0008404572,0.001430928,0.0007918888,0.003236911,0.002735348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008396335,"about_ca_system_score_gemma":0.0009460404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008252403,"about_ca_topic_score_gemma":0.001186593,"domain_scores_codex":[0.9987759,0.0002897405,0.0001295417,0.0002773142,0.0003634742,0.0001639937],"domain_scores_gemma":[0.9994017,0.0001030687,0.0001121995,0.0001630651,0.00008308236,0.0001369189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009918364,0.001537164,0.0009790077,0.0005973279,0.00007520776,0.0003968573,0.000170339,0.001213577,0.9478709,0.01091258,0.004322845,0.03093224],"study_design_scores_gemma":[0.0003149886,0.006689956,0.00259323,0.0002536662,0.0002945018,0.002338007,0.0001130281,0.00570941,0.8165429,0.003356999,0.1617005,0.00009277152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3983654,0.03086775,0.4731616,0.004253772,0.003117045,0.004868438,0.01503247,0.008972413,0.06136113],"genre_scores_gemma":[0.5905038,0.02926961,0.300824,0.001958844,0.0004279781,0.008152401,0.01324027,0.00100618,0.05461696],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007557935,"threshold_uncertainty_score":0.02528381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0634921819755987,"score_gpt":0.3927373720368014,"score_spread":0.3292451900612027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}