{"id":"W4406978407","doi":"10.1016/j.molp.2025.01.022","title":"Discovery of three cytochrome P450 monooxygenase prenyl cyclases that catalyze the final step of glyceollin biosynthesis in soybean","year":2025,"lang":"en","type":"article","venue":"Molecular Plant","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; Agriculture and Agri-Food Canada; Western University","funders":"Agriculture and Agri-Food Canada","keywords":"Monooxygenase; Prenylation; Biology; Prenyltransferase; Cytochrome P450; Biosynthesis; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698413,0.0002366107,0.0002092391,0.0002454619,0.0001931622,0.0003056889,0.0001326881,0.0004658905,0.0006716886],"category_scores_gemma":[0.0002037356,0.0001173517,0.0004343487,0.0001620341,0.0001598285,0.0002656317,0.000198232,0.000625008,0.0002743762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000433722,"about_ca_system_score_gemma":0.000390087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001370529,"about_ca_topic_score_gemma":0.001779646,"domain_scores_codex":[0.9999031,0.00001026077,0.000006439793,0.00002917408,0.00002608711,0.00002491052],"domain_scores_gemma":[0.9999142,0.00001145184,0.00002067682,0.000007775734,0.00001658918,0.0000293667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002189362,0.00002672126,0.001066825,0.00005342965,0.000009425301,0.0001877068,0.00003652025,0.0001054506,0.9920649,0.0005623802,0.0001043909,0.005563376],"study_design_scores_gemma":[0.0001105224,0.0007439603,0.03558199,0.00002739803,0.0000962876,0.001911507,0.0002072917,0.003679341,0.9374799,0.001661233,0.01845049,0.00005007517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578265,0.01092995,0.02265126,0.001242572,0.0001590333,0.0001174774,0.002211444,0.00014022,0.00472154],"genre_scores_gemma":[0.9803346,0.00261818,0.01129832,0.0001792332,0.00002819039,0.00002156211,0.002722718,0.00001248997,0.002784649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001370529,"threshold_uncertainty_score":0.003146946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782452060422508,"score_gpt":0.2353738277208587,"score_spread":0.2175493071166336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}