{"id":"W4407025427","doi":"10.21203/rs.3.rs-5919930/v1","title":"Perflutren lipid microspheres for echocardiogram contrast: A clinical case of anaphylaxis to the non-PEGylated component","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Hospital; Health Sciences Centre; Sunnybrook Health Science Centre; Western University","funders":"","keywords":"Anaphylaxis; Medicine; PEG ratio; Allergy; Immunology; Business","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067925,0.002382951,0.001255271,0.001124133,0.001553774,0.001612876,0.001164482,0.009554313,0.002633174],"category_scores_gemma":[0.005254797,0.001028338,0.001625216,0.0006823494,0.001639331,0.001367438,0.0009788414,0.00485539,0.001161424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001537859,"about_ca_system_score_gemma":0.0006714622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00126257,"about_ca_topic_score_gemma":0.0007680261,"domain_scores_codex":[0.9992506,0.0001326057,0.00007080221,0.0002059398,0.0001431139,0.0001969776],"domain_scores_gemma":[0.9976826,0.001079733,0.0003790256,0.0002243292,0.0001165478,0.0005177021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001431476,0.00008560239,0.001639827,0.0000291838,0.00001131242,0.9956918,0.0001358685,0.0000713377,0.0009023175,0.0001764095,0.0002896524,0.0008235101],"study_design_scores_gemma":[0.0000749902,0.0004372738,0.003380433,0.00001847419,0.00004153083,0.9917115,0.00008428063,0.0007004419,0.002042394,0.0001986806,0.001292991,0.00001705938],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9511162,0.005842102,0.0113772,0.01104588,0.0008941689,0.0006080798,0.000304389,0.0003799489,0.018432],"genre_scores_gemma":[0.9888284,0.001141933,0.001873564,0.004458322,0.00101011,0.00004693757,0.00008881839,0.00006059754,0.002491362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009554313,"threshold_uncertainty_score":0.01115799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1036075859176863,"score_gpt":0.4891444451415266,"score_spread":0.3855368592238403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}