{"id":"W4407073488","doi":"10.5051/jpis.2403080154","title":"Conditioned medium from cultured cementoblasts upregulates amelotin gene expression via the SOCS3 signaling pathway","year":2025,"lang":"en","type":"article","venue":"Journal of Periodontal & Implant Science","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science","keywords":"Cementoblast; SOCS3; Cell biology; Signal transduction; Chemistry; Biology; Medicine; Dentistry; STAT3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000431221,0.00018856,0.0003394075,0.0001742224,0.0006235685,0.0001682904,0.0003238116,0.00006592915,0.0001755609],"category_scores_gemma":[0.000106901,0.0001043695,0.0001609372,0.0003652388,0.0003649933,0.000393588,0.00009322986,0.0002170131,0.00001422268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002566579,"about_ca_system_score_gemma":0.0005880517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006514363,"about_ca_topic_score_gemma":0.00004617552,"domain_scores_codex":[0.9980336,0.00005686826,0.0005321776,0.0002501708,0.0008352554,0.0002919557],"domain_scores_gemma":[0.9988711,0.0000662662,0.0003458492,0.000211176,0.0002787888,0.0002267844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002255069,0.0001364418,0.004239305,0.000006611285,0.00006293645,0.0001469954,0.001113076,0.00002808011,0.9921494,0.00003520623,0.0005291929,0.001327292],"study_design_scores_gemma":[0.001781238,0.0002693428,0.05033202,0.0002931477,0.00008308324,0.0008697348,0.0008037827,0.0001978306,0.9440739,0.0001020153,0.00109053,0.0001034384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949209,0.0006093718,0.001793595,0.001299054,0.000881435,0.000223198,0.00004226156,0.00001787306,0.0002122766],"genre_scores_gemma":[0.9963008,0.00003213012,0.002309483,0.0006769829,0.0001971845,0.000006834748,0.00003389712,0.000007609307,0.0004350874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04807552,"threshold_uncertainty_score":0.4796048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01240038032739354,"score_gpt":0.2806539244473447,"score_spread":0.2682535441199512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}