{"id":"W4407092905","doi":"10.1111/vox.13802","title":"Is there a need for an alternative source of red blood cells for clinical transfusion and will gene‐edited pigs fulfil that need?","year":2025,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital; Canadian Blood Services; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; American Society of Nephrology; U.S. Department of Health and Human Services","keywords":"Blood product; Economic shortage; Pandemic; Population; Medicine; Donation; Blood donations; Blood donor; Intensive care medicine; Environmental health; Coronavirus disease 2019 (COVID-19); Immunology; Disease; Economic growth; Surgery; Infectious disease (medical specialty); Economics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000439003,0.0001699213,0.00044763,0.0001700958,0.00007788176,0.00001579951,0.0001068134,0.0001759926,0.00006907142],"category_scores_gemma":[0.0001420846,0.0001414302,0.0002324581,0.0001630869,0.0001058823,0.00007879018,0.00001168195,0.0001182522,9.82696e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009652666,"about_ca_system_score_gemma":0.00009834512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001003536,"about_ca_topic_score_gemma":0.00001406186,"domain_scores_codex":[0.9987627,0.0001129985,0.0004533147,0.0003162592,0.0001555522,0.0001991795],"domain_scores_gemma":[0.9986124,0.0006834485,0.0001245218,0.0002750507,0.0001936443,0.0001109102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03394241,0.001867607,0.02795182,0.001487782,0.001504229,0.0000182086,0.01490107,0.000007288974,0.8625864,0.0001875395,0.02095592,0.03458969],"study_design_scores_gemma":[0.0325007,0.00516045,0.04608552,0.0006360267,0.001750812,0.00002663137,0.00379027,0.003290392,0.8334942,0.0002613583,0.0726344,0.0003692261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837751,0.001076237,0.01047242,0.002318067,0.0002983083,0.001392564,0.0002985655,0.00004863018,0.0003200755],"genre_scores_gemma":[0.9900885,0.001878583,0.003195441,0.001851302,0.0001735721,0.00007704845,0.0001266802,0.00003643062,0.002572475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05167849,"threshold_uncertainty_score":0.5767354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04842222029881992,"score_gpt":0.3548134675058861,"score_spread":0.3063912472070662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}