{"id":"W4407097948","doi":"10.3390/toxins17020064","title":"Neurotoxins Acting on TRPV1—Building a Molecular Template for the Study of Pain and Thermal Dysfunctions","year":2025,"lang":"en","type":"review","venue":"Toxins","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agence de l'innovation de Défense; Canadian Institute for Theoretical Astrophysics; Institut National de la Santé et de la Recherche Médicale; Conseil Régional des Pays de la Loire; Agence Nationale de la Recherche; Universite Angers","keywords":"TRPV1; Chemistry; Biochemistry; Transient receptor potential channel; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005734091,0.0003189163,0.0007025397,0.0002051534,0.0004462462,0.00005842474,0.0003692289,0.0001260797,0.00001518705],"category_scores_gemma":[0.001004895,0.0001899297,0.0002974402,0.0004504484,0.00006242347,0.00004135132,0.0001387478,0.0003786665,0.000002131103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002727535,"about_ca_system_score_gemma":0.00008719891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001680958,"about_ca_topic_score_gemma":0.000005199624,"domain_scores_codex":[0.9979889,0.0005751694,0.0004281969,0.0005194627,0.0002153483,0.0002729378],"domain_scores_gemma":[0.9959436,0.003367571,0.0003019596,0.0003151538,0.00002283945,0.000048847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001849739,0.0002983673,4.558047e-7,0.003357631,0.00006832919,0.00001004351,0.0004754319,0.0001674125,0.002134294,0.0004448614,0.0001590039,0.9928657],"study_design_scores_gemma":[0.0007514184,0.001741121,0.000002399783,0.006142252,0.0008436925,0.00001441043,0.0005219871,0.0007362436,0.004315464,0.00003065452,0.9843712,0.0005290927],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02041826,0.9505675,0.004054901,0.0003377081,0.003948397,0.0185153,0.0002749171,0.0002613105,0.001621675],"genre_scores_gemma":[0.04553043,0.9513574,0.00004924615,0.0003659003,0.0002619429,0.001213297,0.000003642693,0.0001027993,0.001115317],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9923366,"threshold_uncertainty_score":0.7745108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08438881706128047,"score_gpt":0.3583135206583965,"score_spread":0.273924703597116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}