{"id":"W4407121837","doi":"10.1053/j.gastro.2025.01.237","title":"Mirikizumab for Crohn’s Disease: Small Step Forward or Giant Leap Ahead?","year":2025,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"South Health Campus; University of Calgary","funders":"","keywords":"Crohn's disease; Medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00544328,0.0009187331,0.002607729,0.0008835937,0.0008249721,0.003662746,0.001603794,0.005488639,0.01793738],"category_scores_gemma":[0.005611654,0.0003773491,0.001756583,0.0007324915,0.002074406,0.007824483,0.001833234,0.01231743,0.00641187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001284361,"about_ca_system_score_gemma":0.003113182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001326996,"about_ca_topic_score_gemma":0.004475447,"domain_scores_codex":[0.9982855,0.0005596219,0.0002392808,0.0001881953,0.0003680286,0.0003592513],"domain_scores_gemma":[0.9949602,0.002120425,0.0004333558,0.0001893303,0.0009364607,0.001360287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005881872,0.0007270654,0.002183241,0.003055962,0.0006202377,0.001698362,0.0001747133,0.0006826475,0.003351591,0.02146881,0.2245921,0.7355633],"study_design_scores_gemma":[0.005002747,0.005475397,0.007358476,0.006829681,0.00115151,0.003248663,0.001159343,0.001948673,0.001775416,0.0531049,0.9125746,0.0003705703],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.007136168,0.6214032,0.003075139,0.3330337,0.02358369,0.00009183487,0.0003919706,0.0003788738,0.01090544],"genre_scores_gemma":[0.1140898,0.5593305,0.01429972,0.2280896,0.05871242,0.0003184864,0.0009232574,0.0002504238,0.02398586],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01793738,"threshold_uncertainty_score":0.06000644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009888633173226673,"score_gpt":0.2530522946540626,"score_spread":0.243163661480836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}