{"id":"W4407132939","doi":"10.1159/000543162","title":"Cardiovascular and Renal Outcomes with Ertugliflozin by Baseline Use of Renin-Angiotensin-Aldosterone System Inhibitors or Diuretics, Including Mineralocorticoid Receptor Antagonist: Analyses from the VERTIS CV Trial","year":2025,"lang":"en","type":"article","venue":"Kidney Diseases","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"European Association for the Study of Diabetes; European Foundation for the Study of Diabetes; Pfizer; American Diabetes Association","keywords":"Mineralocorticoid receptor; Renin–angiotensin system; Aldosterone; Medicine; Internal medicine; Endocrinology; Mineralocorticoid; Pharmacology; Urology; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005196732,0.0007062316,0.001781826,0.0003030861,0.0003049553,0.0009530871,0.0006277075,0.0006342579,0.003035912],"category_scores_gemma":[0.004625841,0.0002394546,0.002887053,0.0007073825,0.0005204736,0.0005759679,0.0005672183,0.001104518,0.0001830863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004669723,"about_ca_system_score_gemma":0.0006472678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001940459,"about_ca_topic_score_gemma":0.004488715,"domain_scores_codex":[0.997196,0.001588632,0.0002807212,0.0004211691,0.0003182632,0.0001953875],"domain_scores_gemma":[0.9965336,0.00146442,0.0009373469,0.0004527788,0.0001876712,0.0004240964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7241574,0.0008857414,0.2099994,0.002265493,0.0242469,0.0001935636,0.0002049124,0.001671117,0.003105335,0.0005154849,0.003919881,0.02883486],"study_design_scores_gemma":[0.3092234,0.03470233,0.6154474,0.0005797243,0.02726735,0.0005584274,0.0002411216,0.002815436,0.001567595,0.001479868,0.005968577,0.0001488886],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857691,0.008942055,0.0002791466,0.0002755881,0.0001074367,0.0002301439,0.002236003,0.00001604078,0.002144652],"genre_scores_gemma":[0.9933194,0.001429248,0.0003803519,0.0002402552,0.0001657387,0.0003732528,0.003375279,0.000007992516,0.000708455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005196732,"threshold_uncertainty_score":0.02748328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03124490371837703,"score_gpt":0.2812930656861882,"score_spread":0.2500481619678112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}