{"id":"W4407136520","doi":"10.1083/jcb.202311194","title":"ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression","year":2024,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université Laval; PROTEO; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Cell biology; Mitosis; Biology; Cell cycle; Guanine nucleotide exchange factor; RHOA; Cyclin A; Actin cytoskeleton; Cyclin B; Cyclin B1; Cell; GTPase; Cyclin; Cyclin-dependent kinase 1; Signal transduction; Cytoskeleton; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008887365,0.0004581225,0.0001871253,0.0004818407,0.0002251285,0.000330063,0.0002357963,0.0002138364,0.001457233],"category_scores_gemma":[0.000087152,0.000133572,0.0001903347,0.0001366238,0.000233949,0.0001553018,0.0002548504,0.0002810666,0.000561373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004204147,"about_ca_system_score_gemma":0.000255276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007031427,"about_ca_topic_score_gemma":0.001365513,"domain_scores_codex":[0.9999232,0.00001743522,0.00000544568,0.0000157819,0.00001559252,0.00002242081],"domain_scores_gemma":[0.9999163,0.000007925523,0.00003272296,0.00000932842,0.00001112729,0.00002253443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002009777,0.00001615905,0.0007540029,0.0000266722,0.000007009382,0.0001268545,0.000007366007,0.0001393535,0.9965873,0.0002382565,0.00008929499,0.001806732],"study_design_scores_gemma":[0.00002635507,0.00009458297,0.01073964,0.000006917407,0.00001577327,0.0003841303,0.00002698243,0.001480639,0.9823695,0.0001238634,0.004726466,0.000005118927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950778,0.00126807,0.00155827,0.00007700555,0.00001803671,0.000009958462,0.0003872941,0.0001375422,0.001465983],"genre_scores_gemma":[0.9931699,0.000714895,0.00151401,0.00003095579,0.000006876924,0.00001656755,0.0005741771,0.00004393039,0.003928646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001457233,"threshold_uncertainty_score":0.004874945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004764850473236168,"score_gpt":0.2489752799690427,"score_spread":0.2442104294958066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}