{"id":"W4407166844","doi":"10.20944/preprints202502.0290.v1","title":"An RB1CC1 Missense Variant in Nova Scotia Duck Tolling Retrievers with Degenerative Encephalopathy","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Nova scotia; Missense mutation; Anatomy; Biology; Medicine; Geography; Genetics; Mutation; Archaeology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338395,0.000529314,0.0004127072,0.0008029199,0.0005755973,0.0003410607,0.0003444195,0.0007347867,0.001199728],"category_scores_gemma":[0.0005541471,0.0001733994,0.0003194697,0.0004463026,0.0004771245,0.00007240277,0.000306598,0.0003328942,0.0003807193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00105201,"about_ca_system_score_gemma":0.0002439312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04927572,"about_ca_topic_score_gemma":0.08900572,"domain_scores_codex":[0.9997899,0.00001162651,0.00002483699,0.00007467512,0.00005377421,0.00004524517],"domain_scores_gemma":[0.999697,0.00006108577,0.00009485931,0.00001816797,0.00004610806,0.00008281899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.001950246,0.0002225935,0.3505403,0.0002888676,0.0003305698,0.4216801,0.002869436,0.0009666902,0.2037474,0.0002969679,0.002076687,0.01503017],"study_design_scores_gemma":[0.0000682269,0.0002709778,0.8980729,0.00005348887,0.00008980332,0.09360357,0.0003614373,0.0005515215,0.004672986,0.00004458299,0.002183385,0.00002713638],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983407,0.0002041318,0.0001325973,0.00004927423,0.00001396224,0.00001813735,0.0003882518,0.0000125766,0.0008404894],"genre_scores_gemma":[0.9988241,0.00006218001,0.0001326423,0.00004327979,0.000006014591,0.000003489943,0.000293804,0.000005916196,0.0006284229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04927572,"threshold_uncertainty_score":0.09797782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05452494109264692,"score_gpt":0.325134414729767,"score_spread":0.2706094736371201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}