{"id":"W4407177524","doi":"10.7554/elife.99988.3.sa0","title":"eLife Assessment: Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Astrocyte; Psychology; Stress (linguistics); Neuroscience; Developmental psychology; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002699389,0.0003821976,0.0003159386,0.0003160769,0.0004063764,0.0005002167,0.0003184744,0.0005074498,0.005410538],"category_scores_gemma":[0.0008383751,0.0001387611,0.0002410955,0.0001547737,0.0004416434,0.000249694,0.0005230203,0.000847397,0.0009218644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004106122,"about_ca_system_score_gemma":0.0007783523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003352701,"about_ca_topic_score_gemma":0.009699074,"domain_scores_codex":[0.9997398,0.00003221134,0.00001168577,0.0000443001,0.00009584018,0.00007612163],"domain_scores_gemma":[0.9996052,0.00003414794,0.0001023388,0.00002637664,0.0001337799,0.00009803962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006815779,0.0012531,0.09148133,0.0007425506,0.0002720656,0.01183546,0.001681468,0.0002630407,0.6684331,0.00111593,0.01606,0.2000462],"study_design_scores_gemma":[0.0001216903,0.00229378,0.8397254,0.0002210861,0.0001369791,0.006321953,0.003148066,0.0006984766,0.1241449,0.001929595,0.0211922,0.00006591946],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9809783,0.002189316,0.003184004,0.00218731,0.0005120671,0.0001642173,0.0007106781,0.000167768,0.009906403],"genre_scores_gemma":[0.9801511,0.001365655,0.001538815,0.0005717311,0.0001211773,0.0001115065,0.0005532587,0.00003336119,0.01555348],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.005410538,"threshold_uncertainty_score":0.01810008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06006395664464342,"score_gpt":0.3142046103496752,"score_spread":0.2541406537050317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}