{"id":"W4407184001","doi":"10.1007/s40259-025-00706-4","title":"TL1A Inhibition in Inflammatory Bowel Disease: A Pipeline Review","year":2025,"lang":"en","type":"review","venue":"BioDrugs","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Inflammatory bowel disease; Medicine; Molecular medicine; Internal medicine; Disease; Pharmacology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008443837,0.001119372,0.002341341,0.00179827,0.0002488903,0.001252747,0.001079889,0.001336953,0.005332483],"category_scores_gemma":[0.0009717456,0.0003599708,0.0009747238,0.001553013,0.000439683,0.001156619,0.0008241609,0.003177727,0.002214956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006006125,"about_ca_system_score_gemma":0.001202394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008943893,"about_ca_topic_score_gemma":0.002414729,"domain_scores_codex":[0.999828,0.00003149126,0.00002400914,0.00003069147,0.00005631669,0.00002964564],"domain_scores_gemma":[0.9996629,0.0001651436,0.00004533293,0.000008665343,0.00007359489,0.00004442131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003712082,0.0001651266,0.0001017557,0.01913131,0.0001987879,0.0001864352,0.00003768204,0.0005532205,0.002511516,0.003347523,0.06051309,0.9128824],"study_design_scores_gemma":[0.0001967201,0.0004344097,0.0004670332,0.004755829,0.000445438,0.0006075406,0.00003745422,0.0001794717,0.0007921522,0.002054034,0.9899998,0.00003025173],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000111321,0.9984749,0.0001628027,0.0002874704,0.0003138547,0.00001098767,0.00004271578,0.00001422933,0.0005817768],"genre_scores_gemma":[0.0006109087,0.9979392,0.0002293501,0.0004102063,0.0001690796,0.00001611763,0.00006471963,0.000002893622,0.0005576305],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005332483,"threshold_uncertainty_score":0.0178389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137065343003696,"score_gpt":0.2901550140829343,"score_spread":0.2787843606528973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}