{"id":"W4407184156","doi":"10.1101/2025.02.04.636503","title":"Stem cell-specific NF-κB is required for stem cell survival and epithelial regeneration upon intestinal damage","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Regeneration (biology); Stem cell; Cell biology; Cell; Biology; Epithelium; Intestinal epithelium; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472692,0.0003697389,0.000272442,0.0002965915,0.0001650869,0.0003702156,0.0001783772,0.000306748,0.001609238],"category_scores_gemma":[0.000089531,0.0002187913,0.0003013412,0.000126195,0.0003821152,0.000215308,0.0002851626,0.0007343384,0.0007061286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003668302,"about_ca_system_score_gemma":0.0002096251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007635738,"about_ca_topic_score_gemma":0.001067302,"domain_scores_codex":[0.999843,0.00001366479,0.0000134778,0.00003387142,0.00005816163,0.00003775244],"domain_scores_gemma":[0.9998073,0.00001675,0.0000775751,0.00002595268,0.00001886501,0.00005363537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002573389,0.000004760813,0.0001597411,0.00001738163,0.00000194115,0.00002804796,0.00000622927,0.00001653908,0.9993904,0.00006421724,0.00002045132,0.0002645666],"study_design_scores_gemma":[0.000009358256,0.00005201007,0.0106411,0.000009883723,0.000006543254,0.0001858257,0.00004175645,0.0006409376,0.986356,0.00008526922,0.001967846,0.000003298949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859033,0.002445516,0.007186497,0.000169678,0.00004196743,0.00002728147,0.001557228,0.0002380527,0.002430581],"genre_scores_gemma":[0.991055,0.000482278,0.002563999,0.00005552235,0.000007315504,0.00002737965,0.001351824,0.00006453753,0.004392114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001609238,"threshold_uncertainty_score":0.005383432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095551561931739,"score_gpt":0.2181728223042659,"score_spread":0.1972173066849485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}