{"id":"W4407194247","doi":"10.1016/j.stemcr.2025.102406","title":"20 years of stemness: From stem cells to hypertranscription and back","year":2025,"lang":"en","type":"review","venue":"Stem Cell Reports","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Biology; Stem cell; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000952067,0.0008173605,0.001163903,0.002031595,0.0003430098,0.001335367,0.0009289901,0.001436905,0.002921435],"category_scores_gemma":[0.0009121769,0.0002800395,0.0003372078,0.001656932,0.001413288,0.002975434,0.00107122,0.002613781,0.00240336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001139814,"about_ca_system_score_gemma":0.0009962014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001004837,"about_ca_topic_score_gemma":0.001334541,"domain_scores_codex":[0.9997832,0.00003970318,0.00002841756,0.00005029862,0.00007616037,0.00002231979],"domain_scores_gemma":[0.9995146,0.00023737,0.00004268451,0.00002120225,0.0001182588,0.00006592226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001141478,0.00003884113,0.0001996374,0.009748302,0.00005506515,0.000344783,0.0001680774,0.000424221,0.003198063,0.02774693,0.04201535,0.9159466],"study_design_scores_gemma":[0.000006322113,0.00004735263,0.0003705275,0.001666219,0.00002127104,0.0006336673,0.00007569657,0.0000370527,0.0005692166,0.006895729,0.9896622,0.00001468006],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001083366,0.9975642,0.0001609234,0.000911032,0.0003741523,0.000001736427,0.00001265284,0.000007661389,0.0008593657],"genre_scores_gemma":[0.0009805321,0.9966838,0.0001453169,0.0008688704,0.0003553297,0.000004484167,0.00002345199,0.00000359397,0.0009346498],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002921435,"threshold_uncertainty_score":0.009773135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0237226250090526,"score_gpt":0.2793959458893255,"score_spread":0.2556733208802729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}