{"id":"W4407204863","doi":"10.1016/j.ydbio.2025.02.002","title":"Exploring the differentiation potential of EomesPOS mouse trophoblast cells in mid-gestation","year":2025,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Institute of Human Development, Child and Youth Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institute of Child Health and Human Development; National Institutes of Health; Entrepose Contracting","keywords":"Trophoblast; Biology; Blastocyst; Cell biology; Syncytiotrophoblast; Placenta; Inner cell mass; Cytotrophoblast; Population; Placentation; Cellular differentiation; Andrology; Immunology; Embryo; Embryogenesis; Genetics; Fetus; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002526293,0.000231141,0.0002001474,0.0005482984,0.000169478,0.0003281801,0.0001976782,0.0004102464,0.001362643],"category_scores_gemma":[0.0002131288,0.0002664761,0.0001998766,0.0001830251,0.0002108032,0.0002742358,0.0002860443,0.0009310654,0.0007397732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002292663,"about_ca_system_score_gemma":0.0001663797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004935109,"about_ca_topic_score_gemma":0.0009171195,"domain_scores_codex":[0.9998419,0.00002189537,0.00001944425,0.00003323945,0.00005297272,0.00003058473],"domain_scores_gemma":[0.99986,0.00002950213,0.00002904274,0.00001469699,0.00001626272,0.00005040275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001115934,0.00001804822,0.0006328428,0.00002274145,0.000001727901,0.0001238364,0.00006349637,0.00002656725,0.9976237,0.0002166629,0.00002547452,0.001133292],"study_design_scores_gemma":[0.00001922017,0.0005803306,0.02015209,0.00003399832,0.00002496236,0.001182746,0.000188492,0.0009080041,0.9655047,0.0003204019,0.01107597,0.000009088115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771982,0.004239756,0.009720493,0.0001361083,0.00004559257,0.000105439,0.001259003,0.0001404105,0.00715505],"genre_scores_gemma":[0.9698211,0.003763857,0.01022504,0.0001363498,0.00001936675,0.000195615,0.001707101,0.00008155403,0.01404996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001362643,"threshold_uncertainty_score":0.004558504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03189295843124855,"score_gpt":0.2602558675307,"score_spread":0.2283629090994514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}