{"id":"W4407255120","doi":"10.7554/elife.104079.1.sa0","title":"Reviewer #2 (Public review): Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Radiomics and Machine Learning in Medical Imaging","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bioenergetics; Biology; Mitochondrion; Cell biology; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03512068,0.001534983,0.003095892,0.003332219,0.002637433,0.007640894,0.005143018,0.01913059,0.07674079],"category_scores_gemma":[0.2006151,0.00131348,0.003648222,0.002186578,0.002318413,0.004317746,0.003614916,0.007247639,0.03667253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005832087,"about_ca_system_score_gemma":0.01310425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003266404,"about_ca_topic_score_gemma":0.004152567,"domain_scores_codex":[0.9791842,0.006299166,0.003785769,0.002156253,0.007237664,0.001336979],"domain_scores_gemma":[0.7344031,0.03536549,0.01649036,0.008344335,0.1962951,0.009101534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007433463,0.000005984048,0.000105804,0.00165775,0.00002746039,0.00005101758,0.00002836008,0.00001648301,0.00008265545,0.0001154628,0.9918997,0.005934861],"study_design_scores_gemma":[0.0003964895,0.00007667174,0.001673292,0.005347563,0.0001612689,0.0004324286,0.0001701339,0.0001686157,0.0004095449,0.00120479,0.9898831,0.00007612689],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.0004724608,0.01339277,0.001366983,0.3740546,0.5968688,0.001535377,0.004715397,0.0007826705,0.006811022],"genre_scores_gemma":[0.009495786,0.01936853,0.002822731,0.5279338,0.3855359,0.006010142,0.003605108,0.001194403,0.04403346],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.07674079,"threshold_uncertainty_score":0.2567236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05755793962204673,"score_gpt":0.3423713946730697,"score_spread":0.284813455051023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}