{"id":"W4407285187","doi":"10.1093/jcag/gwae059.010","title":"A10 RESTORATION OF ARYL HYDROCARBON RECEPTOR SIGNALING IN CELIAC DISEASE BY ORAL TRYPTOPHAN SUPPLEMENTATION: AN EXPLORATORY STUDY","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Microbial Metabolites in Food Biotechnology","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aryl hydrocarbon receptor; Tryptophan; Aryl; Disease; Receptor; Chemistry; Medicine; Gastroenterology; Pharmacology; Internal medicine; Biochemistry; Organic chemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00177001,0.000869319,0.001728189,0.0003896834,0.0004638101,0.0008072651,0.000919916,0.00141411,0.005055302],"category_scores_gemma":[0.0008507351,0.0003870193,0.001551389,0.0003646514,0.00107805,0.0005949113,0.0004645311,0.001302911,0.0006317433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006975351,"about_ca_system_score_gemma":0.001316684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001471481,"about_ca_topic_score_gemma":0.002936912,"domain_scores_codex":[0.9993848,0.0002819199,0.00004619598,0.00009695387,0.0000567316,0.000133414],"domain_scores_gemma":[0.9992218,0.0002030535,0.0001091181,0.00007445638,0.00007701023,0.0003144938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8017002,0.1169804,0.003430302,0.002055184,0.00154192,0.0003050587,0.0001931847,0.0002646894,0.03645452,0.0001382161,0.0006592262,0.03627713],"study_design_scores_gemma":[0.2347961,0.7538374,0.006957787,0.00007450263,0.0008412879,0.00008199191,0.00008086243,0.0001466723,0.001974266,0.00007730937,0.001115738,0.00001618159],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993148,0.003077708,0.0002840407,0.0001703439,0.00009359472,0.002215755,0.0003503096,0.00002271231,0.0006374695],"genre_scores_gemma":[0.9931753,0.001922819,0.0007006501,0.0003453455,0.0001617753,0.001879145,0.0003192973,0.000004902216,0.001490697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005055302,"threshold_uncertainty_score":0.01691169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009266482415362477,"score_gpt":0.2568992302337536,"score_spread":0.2476327478183911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}