{"id":"W4407285727","doi":"10.1093/jcag/gwae059.215","title":"A215 INJECTION SITE PAIN AND ADHERENCE IN PATIENTS SWITCHING FROM REFERENCE ADALIMUMAB TO AVT02 – INTERIM RESULTS OF THE EASE PAIN TRIAL.","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster Children's Hospital; McGill University Health Centre","funders":"","keywords":"Interim; Adalimumab; Medicine; Extended release; Interim analysis; Physical therapy; Clinical trial; Internal medicine; Pharmacology; History; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00407235,0.0005685537,0.001366146,0.000287803,0.00065424,0.001248782,0.000597599,0.001272548,0.003098296],"category_scores_gemma":[0.003885943,0.0003602694,0.00211054,0.0005064008,0.0004244241,0.0006987632,0.0004619294,0.001725344,0.0004602627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008576342,"about_ca_system_score_gemma":0.001082047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003428503,"about_ca_topic_score_gemma":0.005161922,"domain_scores_codex":[0.9972031,0.001602868,0.0001907579,0.0002997248,0.0003669238,0.0003365708],"domain_scores_gemma":[0.9966817,0.0006654865,0.0009963922,0.0003302299,0.0002729224,0.001053285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7590699,0.03242831,0.1288294,0.0006213026,0.005143748,0.0001523443,0.0002682858,0.0005033792,0.002433516,0.0001166953,0.004022104,0.066411],"study_design_scores_gemma":[0.2863822,0.2703405,0.4347676,0.0001110754,0.003445527,0.0002462761,0.0002350571,0.001261996,0.0006719845,0.0001674517,0.002290064,0.00008022347],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955764,0.001652249,0.00007240243,0.0001479255,0.00007813011,0.0004124546,0.0007135581,0.00001362455,0.001333436],"genre_scores_gemma":[0.9963032,0.0003429137,0.0002372948,0.0003516703,0.0001603472,0.0004657141,0.001413033,0.000003268952,0.0007225787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00407235,"threshold_uncertainty_score":0.02153695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02557297855539016,"score_gpt":0.3046364246171583,"score_spread":0.2790634460617682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}