{"id":"W4407285828","doi":"10.1093/jcag/gwae059.120","title":"A120 METHYLGLYOXAL (MGO) AS A SUBSTRATE FOR LACTYLATION IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Methylglyoxal; Esophageal squamous cell carcinoma; Substrate (aquarium); Basal cell; Cancer research; Internal medicine; Medicine; Chemistry; Carcinoma; Oncology; Biochemistry; Biology; Enzyme; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207441,0.0003533823,0.0002525758,0.0002309758,0.0001546467,0.0002206371,0.000159615,0.0002564007,0.0009130634],"category_scores_gemma":[0.0001019404,0.0001084853,0.0003505716,0.0002668351,0.0001310543,0.0001746314,0.0001860848,0.0002893227,0.0002619015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000240233,"about_ca_system_score_gemma":0.0001147435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005218096,"about_ca_topic_score_gemma":0.0005881899,"domain_scores_codex":[0.9998872,0.0000240088,0.00001137196,0.00002582237,0.00002582198,0.00002576206],"domain_scores_gemma":[0.9999381,0.000007739573,0.00001942487,0.000005643529,0.00001109255,0.00001799439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002291134,0.00001685465,0.0006632904,0.00006769434,0.000008976502,0.00005171707,0.000008804198,0.00004075677,0.9975567,0.00001701121,0.00003058121,0.001308496],"study_design_scores_gemma":[0.00001812349,0.0004735961,0.01105521,0.00001026479,0.00003799776,0.000280546,0.00004256806,0.0007901959,0.9849914,0.00002562524,0.002269383,0.000005125663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907595,0.005942496,0.001747648,0.00008859555,0.00003342433,0.00003023066,0.0004452541,0.00003955759,0.0009133411],"genre_scores_gemma":[0.9934783,0.001772266,0.002297926,0.00005178761,0.00001119016,0.00003887838,0.0009085118,0.000009211152,0.001431976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009130634,"threshold_uncertainty_score":0.00305444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007732161585030925,"score_gpt":0.2662283367397935,"score_spread":0.2584961751547625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}