{"id":"W4407285832","doi":"10.1093/jcag/gwae059.140","title":"A140 DUPILUMAB IMPROVED HISTOLOGY, CLINICAL SYMPTOMS, AND ENDOSCOPIC FEATURES IN ADULTS AND ADOLESCENTS WITH EOSINOPHILIC ESOPHAGITIS THROUGH 52 WEEKS REGARDLESS OF BASELINE DISEASE DURATION: POST-HOC SUBGROUP ANALYSIS OF THE PHASE 3 LIBERTY EOE TREET STUDY","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Eosinophilic esophagitis; Medicine; Dupilumab; Post-hoc analysis; Post hoc; Subgroup analysis; Internal medicine; Histology; Disease; Gastroenterology; Dermatology; Confidence interval; Asthma","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002578479,0.0007246748,0.002434323,0.0002208077,0.0002336739,0.0008122718,0.0004616107,0.0005697808,0.002148161],"category_scores_gemma":[0.001515446,0.0003320774,0.003237095,0.0002622258,0.0003446486,0.0005737675,0.0004482654,0.001178084,0.0002156544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000497082,"about_ca_system_score_gemma":0.0007316414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008592264,"about_ca_topic_score_gemma":0.003094421,"domain_scores_codex":[0.9991073,0.0004436698,0.00007675352,0.0001519156,0.00008416086,0.0001361474],"domain_scores_gemma":[0.9990096,0.000305399,0.0002941212,0.00009357156,0.00008084378,0.0002163492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8895439,0.003217923,0.04615641,0.001142849,0.01145857,0.0001493096,0.0001514996,0.000706738,0.006882126,0.00007894031,0.001646254,0.03886546],"study_design_scores_gemma":[0.3247204,0.3025093,0.345552,0.0002630908,0.01759351,0.000568154,0.0002256761,0.002766222,0.002622687,0.0002015981,0.002904028,0.00007330789],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953347,0.003065147,0.0001386241,0.00008830377,0.00003802058,0.0002698601,0.0006588426,0.0000135587,0.0003930361],"genre_scores_gemma":[0.9973171,0.0006072022,0.0003137325,0.0001534829,0.00005119354,0.0003759311,0.0007445144,0.000005670438,0.0004310478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002578479,"threshold_uncertainty_score":0.01363647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005290349442909417,"score_gpt":0.2657731374107877,"score_spread":0.2604827879678783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}