{"id":"W4407286477","doi":"10.1093/jcag/gwae059.249","title":"A249 PROTON PUMP INHIBITOR USE AND RISK OF DEMENTIA: AN UMBRELLA REVIEW OF SYSTEMATIC REVIEWS AND META-ANALYSES","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Dementia; Meta-analysis; Systematic review; Medicine; Proton-pump inhibitor; MEDLINE; Internal medicine; Chemistry; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04757908,0.003150933,0.02055531,0.02139797,0.00120146,0.006640216,0.003376338,0.003126669,0.004829323],"category_scores_gemma":[0.1298686,0.002216531,0.02466526,0.0185151,0.001297614,0.003837795,0.00317707,0.001914813,0.0006195516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004935097,"about_ca_system_score_gemma":0.009129091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00654431,"about_ca_topic_score_gemma":0.01556936,"domain_scores_codex":[0.9398165,0.02886539,0.02122547,0.003250649,0.006109077,0.0007330826],"domain_scores_gemma":[0.8924392,0.08162881,0.01808969,0.002786724,0.00459895,0.0004566421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0003508053,0.00001551051,0.001351916,0.7927033,0.1847277,0.00008366181,0.0001461139,0.0002449913,0.0001681589,0.0003774913,0.001203593,0.01862659],"study_design_scores_gemma":[0.0004930477,0.0002372574,0.003487462,0.4077539,0.5753924,0.0001920517,0.0001487325,0.0003224333,0.0002115831,0.001147036,0.01056479,0.00004937698],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006587729,0.9971813,0.0005452756,0.000350389,0.0002180708,0.0004196778,0.0003746403,0.00001577649,0.0002361804],"genre_scores_gemma":[0.03134206,0.9567677,0.005242181,0.001604136,0.0004698276,0.003747245,0.0005431593,0.00002689776,0.0002567729],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.04757908,"threshold_uncertainty_score":0.2516252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08188060130210513,"score_gpt":0.3490466694525537,"score_spread":0.2671660681504486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}