{"id":"W4407286905","doi":"10.1093/jcag/gwae059.246","title":"A246 EXPLORING THE ROLE OF LUMINAL PROTEASES IN NOCICEPTION MODULATION FROM PATIENTS WITH ACTIVE AND REMISSIVE INFLAMMATORY BOWEL DISEASE","year":2025,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Ophthalmology and Eye Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Inflammatory bowel disease; Proteases; Medicine; Nociception; Modulation (music); Internal medicine; Disease; Chemistry; Biochemistry; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002258393,0.0002509077,0.0004412866,0.0002618476,0.0002200039,0.0003976704,0.0001092638,0.0003299435,0.002830427],"category_scores_gemma":[0.0005161874,0.00009648081,0.0002328269,0.0001929804,0.0002136837,0.0002011976,0.0002283714,0.0003983769,0.0002981958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001197279,"about_ca_system_score_gemma":0.0001235725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003361081,"about_ca_topic_score_gemma":0.0004043128,"domain_scores_codex":[0.9998653,0.00003101709,0.0000187051,0.00003096262,0.00002446357,0.00002953803],"domain_scores_gemma":[0.9998053,0.00003562264,0.00006298515,0.000009937948,0.00002762387,0.00005862922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01729821,0.001072594,0.3312596,0.00106853,0.0002974034,0.0045221,0.001083044,0.0002211168,0.5787508,0.0001579982,0.001280021,0.06298867],"study_design_scores_gemma":[0.0002093368,0.006538599,0.9625286,0.00008404125,0.0001401723,0.004390699,0.00086767,0.0005497132,0.02194321,0.0001181296,0.002614186,0.00001563434],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974491,0.001639091,0.0001837825,0.00008031377,0.00001604955,0.00001851589,0.0001570586,0.000005534567,0.0004505866],"genre_scores_gemma":[0.9987236,0.000386249,0.0001868364,0.00008047039,0.00001957825,0.00001765473,0.0002637838,0.000001629281,0.0003202676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002830427,"threshold_uncertainty_score":0.009468675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005001686177080893,"score_gpt":0.2075778399192502,"score_spread":0.2025761537421693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}